Book takes you to the exact room at that rate on HotelDupe's booking partner. Confirmation arrives by email; manage or cancel any time from Find your booking.
The honest take
Book the St. Regis. It rates higher (9.4 vs 9.1 across far more reviews, 330 to 194), and costs $1,044 against Six Senses' $1,527. Both are 5-star and central, but the St. Regis undercuts by nearly a third while outperforming on guest satisfaction and facilities including a health club and spa. Six Senses is newer and fashionable, but on the numbers alone this isn't close.
The look and the feel
Six Senses Rome
Six Senses Rome opened inside a restored 16th-century palazzo on Piazza San Marcello, and the brand's signature is a kind of pared-back, wellness-forward luxury: limestone, warm timber, biophilic touches, low lighting, a spa culture built into the bones of the place rather than bolted on as an afterthought. The public rooms favour texture over gilt, terracotta and linen over marble and gold leaf, and the terrace looks over Roman rooftops rather than a grand boulevard. It draws a design-literate, discreetly wealthy crowd who want five-star comfort without the chandeliers.
Six Senses suits travellers who want contemporary, spa-led luxury and a quieter, design-forward aesthetic tucked into the historic centre.
The St. Regis Rome
The St. Regis Rome, opened in 1894 as the Grand Hotel by César Ritz, is Belle Époque through and through: gilt mirrors, frescoed ceilings, crystal chandeliers, a grand staircase that still looks built for a diplomatic entrance. The Writing Room and the bar carry that old European hotel formality, all brocade and polished brass, and the location near Piazza della Repubblica and the Via Veneto puts it in the thick of Rome's 19th-century boulevard grandeur rather than its medieval alleys. It suits guests who want the theatre of an old grand hotel, and to feel history in the fabric of the building.
The St. Regis suits travellers who want the full grand-hotel experience, ornate interiors, and proven service pedigree, at a lower price than the newer competitor.
On the facility lists neither hotel is shown lacking anything the other has, so the real trade-off is that Six Senses' fresher, wellness-oriented interiors and brand cachet come at a $483-a-night premium over the St. Regis's older but more decorated and higher-rated property.
The St. Regis is the more beautiful room to stand in, its frescoes and chandeliers doing what Six Senses' quiet minimalism deliberately avoids, but Six Senses has the more interesting spatial idea for anyone tired of gilt.
The numbers
Six Senses Rome
The St. Regis Rome
Price, same night
$1,498
$1,204
Guest rating
9.1/10
9.4/10
Reviews
194
330
Stars
★★★★★
★★★★★
Facilities on our list
6
6
Distance apart
1.3 km
What one has that the other doesn't
Only Six Senses Rome has
Nothing on our list that The St. Regis Rome lacks.
Only The St. Regis Rome has
Nothing on our list that Six Senses Rome lacks.
What guests actually say
Six Senses Rome
excellent location
beautiful design and style
friendly and welcoming staff
overpriced for the quality
limited breakfast variety
uncomfortable bed and noise
“The bed was very uncomfortable, and there were constant disturbing noises that made it extremely difficult to rest or sleep properly.”
The St. Regis Rome
impeccable, attentive staff
seamless, warm check-in experience
exceptional service throughout
“Unsurpassed staff, spectacular room, not a thing out of place, And not a single issue of even minor consequence arose during our entire visit.”
The St. Regis guests come away happier, as their reviews consistently praise flawless, personal service with no recurring complaints, while Six Senses guests note issues like noise, price and breakfast variety.
“uncomfortable and absolutely not worth the money.”
Location
From the very beginning, I would strongly advise guests not to rely on the prices shown on Booking.com for this hotel, as the rates are extremely overpriced compared with the actual quality of the stay and service.
The bed was very uncomfortable, and there were constant disturbing noises that made it extremely difficu
10/10
“Such a Great Hotel”
The style of this hotel is beautiful, and the staff are amazing. Everyone was so friendly and welcoming. The location is perfect as well. Overall, it was a wonderful experience, and I really enjoyed my stay
The only downside was the limited variety of food options on the Bivium restaurant menu. I would have appreciated having more choices available.
10/10
“Best hotel in Rome for that level”
Location, design, atmosphere, international jet set, gym and Spa are top notch
The price might be exaggerated depending on the season but…
We were very fortunate to stay at The St Regis for a few nights before our cruise and it did not disappoint. The service and attention to detail was immaculate throughout our stay. Overall our experience was fantastic, luxurious and elegant. Highly recommended
10/10
“Over the Top!”
My wife and I have had the pleasure of staying at high-end hotels around the world for the lat 25 years. The St. Regis Rome was probably the pinnacle of all our past experiences.
Unsurpassed staff, spectacular room, not a thing out of place, And not a single issue of even minor consequence arose during our entire visit.
We've never experienced more friendly and helpful personnel, special kudos to server Marah an
10/10
“Fantastic Experience at St. Regis Rome!”
St. Regis Rome provided the best hotel stay that my family has ever had. From the moment we were welcomed at check-in, the experience was perfect in every way. We recently stayed for a few nights on either end of a side trip to another region of Italy, and the entire staff - from the head of guest relations to housekeeping - made it feel like our home away from home. We will never stay anywhere else in Rome, and pl
Luxurious Amenities Six Senses Rome offers a 5-star experience with a terrace, restaurant, bar, sauna, and evening entertainment. Enjoy the convenience of room service and a concierge service during your stay. Elegant Rooms Indulge in comfort with air-conditioned rooms featuring modern amenities like a flat-screen TV, safety deposit box, and coffee machine.…
Check-in — · Check-out 12:00 PM
The St. Regis Rome
Luxurious Accommodation in Rome's Historic Centre Experience the epitome of luxury at the St. Regis Rome, located just steps away from iconic landmarks like Piazza della Repubblica and Via Veneto. Elegant Dining and Relaxation Options Indulge in traditional cuisine, unwind at the health club and spa, and conduct business in style with our prestigious…
Check-in — · Check-out 12:00 PM
Facilities, in full
Six Senses Rome
Fitness facilities
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Restaurant
Room service
Heating
Terrace
Family rooms
Pets allowed
Lift / Elevator
Laundry
The St. Regis Rome
WiFi available
Free WiFi
Parking
Non-smoking rooms
Air conditioning
Fitness center
24-hour front desk
Restaurant
Room service
Business center
Family rooms
Garden
Pets allowed
Lift / Elevator
Laundry
Safety deposit box
Where they are
Piazza San MarcelloVia Vittorio Emanuele Orlando 3
Rates are live for 2026-10-10, one night, two guests, fetched together so the two are comparable. Facilities and reviews are from each hotel's own listing. The honest take is written by our AI from the listing, the reviews and what is widely known about each hotel. HotelDupe earns a commission if you book, which never changes the verdict. All comparisons